In the year 2019, as Earth's human population is outnumbered by vampires (who are always hungry and now low on the red stuff), a leading hematologist (Ethan Hawke) struggles to find a cure for vampirism while tasked with the job of creating a synthetic blood substitute. A new experiment is soon inspired by the appearance of a mysterious nosferatu-cum-human rebel (Willem Dafoe), but time grows dangerously short. With Michael Dorman, Harriet Minto-Day. 98 min. Widescreen (Enhanced); Soundtrack: English Dolby Digital 5.1 EX; Subtitles English, Spanish; art gallery; audio commentary; bonus short "The Big Picture" (2000); "making of" documentary; theatrical trailer.