Gambler "Full-House" Johnny is shot down by an unknown assailant, leaving a trail of debt that leads all the way to Police Commissioner Desmond. Ace reporter Bob Grayson of the Morning Express, investigating the killing, encounters a pretty young female witness trying to keep her family's good name out of the papers. He discovers that she is none other than Myrna Van Buren, the daughter of Morning Express owner Titus Van Buren. When Myrna is falsely accused of the murder, Bob vows to find the real killerand save the woman that he's fallen in love with. Complicating his task is the fact that Myrna's fingerprints are all over the murder weapon. With the help of his friend on the force, Hugo Meyer (Ford Sterling, the legendary Mack Sennett star in one of his final screen roles), Grayson launches a campaign of deception designed to ferret out Johnny's murderer.An excellent example of 1930s' newsroom comedy-drama, The Headline Woman is a remarkable collaboration of several leading motion picture industry talents. The film's editor, Joseph Kane directed hundreds of westerns, while supervising editor Joseph H. Lewis would go on to direct several classics, most notably Gun Crazy (1949) and The Big Combo (1955). Director William Nigh was no stranger to the genre either, contributing solid craftsmanship to hundreds of modestly budgeted films.