More than 800,000 Americans are tired of being dismissed as hypochondriacs. Kim A. Snyder, whose own promising film career was almost sidelined by a four-year bout with it, examines the facts about Chronic Fatigue Syndrome (CFS). Once dismissed as "YuppieFlu," CFS has baffled physicians and patients for decades. With no known cause, it continues to destroy lives, as much because of the way the chronically fatigued are stigmatized. Snyder interviews everyday victims and famous sufferers like soccer star Michelle Akers and Hollywood director Blake Edwards for this telling picture of loss and perseverance.